Endocrine Abstracts

Men with spinal cord injury (SCI) exhibit a prostate volume significantly smaller compared to age-matched able-bodied men1–3. As men with chronic SCI (lasting more than 1 year) also display a very high prevalence of androgen deficiency4,5, a protective role of low testosterone against prostate enlargement could be hypothesized in this population. This study aimed to identify independent determinants of prostate volume in men with chronic SCI. As ass...

Background: Men suffering from spinal cord injury (SCI) were at increased risk for cardiovascular diseases (CVD). SCI subjects showed an higher value of carotid intima media thickness (cIMT) at ultrasound, a surrogate markers of sub-clinical atherosclerosis. Furthermore, SCI men exhibited an higher prevalence of androgen deficiency compared to general population.Objectives: To investigate the relationship between total testosterone (TT) levels and cIMT i...

Background: In patients with Klinefelter syndrome (KS) morbidity and mortality seem to be higher than general population, this depending on a wide number of possible comorbidities. Impaired metabolic profile, increased risk of venous thrombosis and the consequent increase of cardiovascular diseases might play a key role in this condition as well as reduced bone mineral density and higher fracture risk. Nowadays testosterone replacement therapy (TRT) is the first-choice treatme...